Mode of Action
- Naronapride is a novel pro-kinetic agent with a unique combination of both 5HT4 agonistic and D2 antagonistic properties.
- It is locally active in the gut lumen and designed to be minimally absorbable
- Side-effect profile is similar to placebo with no cardiovascular liabilities observed in comprehensive TQT study
NAT-19/GPX (MOVE-IT): Dose-Finding Phase 2 Trial
Study Design

Trial Population
- Women or men between ≥18 and ≤75 years of age
- Idiopathic or diabetic gastroparesis for more than 3 months
- Evidence of delayed gastric emptying
- Absence of mechanical obstructions
Trial Countries

- France
- Belgium
- The Netherlands
- Poland
- Germany
- Switzerland
- Austria
- UK